PMI Impact Malaria




PMI Impact Malaria in Cambodia

PMI Impact Malaria (IM) is the flagship global service delivery project of the U.S. President’s Malaria Initiative (PMI). To advance PMI’s goal of fighting malaria and saving lives, IM is supporting Cambodia’s national malaria control program (NMCP) in its efforts to strengthen malaria service delivery.

IM began working with Cambodia’s NMCP in 2018 to conduct a study testing the performance of a novel point-of-care rapid diagnostic test (RDT) for detecting glucose-6-phosphate dehydrogenase (G6PD) deficiency. Individuals who are G6PD deficient experience adverse health reactions to primaquine, a drug capable of achieving radical cure of Plasmodium vivax infections. The ability to widely and accurately test for G6PD deficiency would allow for appropriate prescribing of primaquine.  

Country Resources

  • Cambodia Malaria Summary PMI Webpage
  • Malaria Service Delivery Photos PMI Impact Malaria Photo Library

Malaria Country Context 

Malaria remains a fact of life for billions of people around the world. Although considerable progress has been made in malaria control in the Greater Mekong Subregion, the spread of antimalarial resistance threatens to undermine these gains. 

In 2018, Cambodia reported only one death due to malaria. Malaria incidence is highest in the Northeastern parts of the country and lower in the Western provinces. Peak transmission is between July and November when the country transitions from the hot season to the rainy one. The malaria parasite species Plasmodium vivax and Plasmodium falciparum are co-endemic. 

Despite successes, the development and spread of resistance to artemisinin drugs, the first-line treatment for malaria in the region, remains a challenge. The country is working to develop evidenced-based approaches that can be scaled up to achieve national elimination of both P. falciparum and multi-drug resistant malaria.  


This is PMI Impact Malaria’s geographic coverage in Cambodia: 


Photo Credit: Kharn Lina/PMI, Cambodia

Sources: PMI’s Cambodia Country BriefPMI’s Cambodia Malaria Operational Plan FY 20202019 World Malaria Report Cambodia Country Profile, PMI Impact Malaria Cambodia, and Cambodia's NMCP